Clayton: Basic Pharmacology for Nurses, 15th Edition

Chapter 1: Definitions, Names, Standards, and Information Sources

Test Bank

MULTIPLE CHOICE

	1.	What is the name under which a drug is listed by the U.S. Food and Drug Administration (FDA)?
A.	Brand	
B.	Nonproprietary	
C.	Official	
D.	Trademark	

ANS:	C

	Feedback	
A	The brand name, or trademark, is the name given to a drug by its manufacturer.	
B	The nonproprietary, or generic, name is provided by the USAN Council.	
C	The official name is the name under which a drug is listed by the FDA.	
D	The trademark, or brand name, is the name given to a drug by its manufacturer.	

DIF:	Cognitive Level: Knowledge	REF:	2	
TOP:	Nursing Process Step: Assessment	
MSC:	NCLEX Client Needs Category: Safe, Effective Care Environment

	2.	Which source contains information specific to nutritional supplements?
A.	USP Dictionary of USAN & International Drug Names	
B.	Natural Medicines Comprehensive Database	
C.	United States Pharmacopoeia/National Formulary (USP-NF)	
D.	Drug Interaction Facts	

ANS:	C

	Feedback	
A	USP Dictionary of USAN & International Drug Names is a compilation of drug names, pronunciation guide, and possible future FDA-approved drugs; it does not include nutritional supplements.	
B	Natural Medicines Comprehensive Database contains evidence-based information on herbal medicines and herbal combination products; it does not include information specific to nutritional supplements.	
C	United States Pharmacopoeia/National Formulary contains information specific to nutritional supplements.	
D	Drug Interaction Facts contains comprehensive information on drug interaction facts; it does not include nutritional supplements.	

DIF:	Cognitive Level: Knowledge	REF:	3	
TOP:	Nursing Process Step: Assessment	
MSC:	NCLEX Client Needs Category: Physiological Integrity

	3.	What is the most comprehensive reference available to research a drug interaction?
A.	Drug Facts and Comparisons	
B.	Drug Interaction Facts	
C.	Handbook on Injectable Drugs	
D.	Martindale—The Complete Drug Reference	

ANS:	B

	Feedback	
A	Drug Facts and Comparisons is not the most comprehensive source.	
B	First published in 1983, this reference is the most comprehensive book available on drug interactions. In addition to monographs listing various aspects of drug interactions, this information is reviewed and updated by an internationally renowned group of physicians and pharmacists with clinical and scientific expertise.	
C	Handbook on Injectable Drugs is not the most comprehensive source.	
D	Martindale—The Complete Drug Reference is not the most comprehensive source.	

DIF:	Cognitive Level: Comprehension	REF:	4	
TOP:	Nursing Process Step: Assessment	
MSC:	NCLEX Client Needs Category: Physiological Integrity

	4.	The physician has written an order for a drug with which the nurse is unfamiliar. Which section of the Physicians’ Desk Reference (PDR) is most helpful to get information about this drug?
A.	Manufacturer’s section	
B.	Brand and Generic Name section	
C.	Product Category section	
D.	Product Information section	

ANS:	B

	Feedback	
A	The Manufacturer’s section is a roster of manufacturers.	
B	A physician’s order would include the brand and/or generic name of the drug. The alphabetic index in the PDR would make this section the most user-friendly. Based on a physician’s order, manufacturer’s information and classification information would not be known.	
C	The Product Category section lists products subdivided by therapeutic classes, such as analgesics, laxatives, oxytocics, and antibiotics.	
D	The Product Information section contains reprints of the package inserts for the major products of manufacturers.	

DIF:	Cognitive Level: Comprehension	REF:	5	
TOP:	Nursing Process Step: Planning	
MSC:	NCLEX Client Needs Category: Physiological Integrity

	5.	Which is the most useful drug reference source for patients?
A.	American Drug Index	
B.	American Hospital Formulary	
C.	Health on the Net Foundation	
D.	Physicians’ Desk Reference	

ANS:	C

	Feedback	
A	The American Drug Index is not appropriate for patient use.	
B	The American Hospital Formulary is not appropriate for patient use.	
C	The Health on the Net Foundation is the most appropriate source for patients to obtain drug information. It is the leading organization to promote and guide the deployment of useful and reliable online medical and health information and its appropriate and efficient use.	
D	The Physicians’ Desk Reference is not appropriate for patient use.	

DIF:	Cognitive Level: Knowledge	REF:	7	
TOP:	Nursing Process Step: Implementation		
MSC:	NCLEX Client Needs Category: Physiological Integrity

	6.	Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
A.	Federal Food, Drug, and Cosmetic Act (1938)	
B.	Durham-Humphrey Amendment (1952)	
C.	Controlled Substances Act (1970)	
D.	Kefauver-Harris Drug Amendment (1962)	

ANS:	A

	Feedback	
A	The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the safety of all drugs before marketing. Later amendments and acts helped tighten FDA control and ensure drug safety.	
B	The Durham-Humphrey Amendment defines the kinds of drugs that cannot be used safely without medical supervision and restricts their sale to prescription by a licensed practitioner.	
C	 The Controlled Substances Act addresses only controlled substances and their categorization.	
D	The Kefauver-Harris Drug Amendment ensures drug efficacy and greater drug safety. Drug manufacturers are required to prove to the FDA the effectiveness of their products before marketing them.	

DIF:	Cognitive Level: Knowledge	REF:	7	
TOP:	Nursing Process Step: Assessment	
MSC:	NCLEX Client Needs Category: Physiological Integrity

	7.	Meperidine (Demerol) is a narcotic with a high potential for physical and psychological dependency. Under which classification does this drug fall?
A.	I	
B.	II	
C.	III	
D.	IV	

ANS:	B
.

	Feedback	
A	Schedule I drugs have high potential for abuse and no recognized medical use.	
B	Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to severe psychological and physical dependence.	
C	Schedule III drugs have some potential for abuse. Use may lead to low-to-moderate physical dependence or high psychological dependence.	
D	Schedule IV drugs have low potential for abuse. Use may lead to limited physical or psychological dependence.	

DIF:	Cognitive Level: Application	REF:	7	
TOP:	Nursing Process Step: Assessment	
MSC:	NCLEX Client Needs Category: Safe, Effective Care Environment

	8.	What would the FDA do to expedite drug development and approval for an outbreak of smallpox, for which there is no known treatment?
A.	List smallpox as a health orphan disease.	
B.	Omit the preclinical research phase.	
C.	Extend the clinical research phase.	
D.	Fast-track the investigational drug.	

ANS:	D

	Feedback	
A	Orphan diseases are not researched in a priority manner.	
B	Preclinical research is not omitted.	
C	Extending any phase of the research would mean a longer time to develop a vaccine.	
D	The FDA must ensure that all phases of the preclinical and clinical research phase have been completed in a safe manner. Once the Investigational New Drug Application has been approved, the drug can receive highest priority within the agency, which is called fast tracking. A smallpox outbreak would become a priority concern in the world.	

DIF:	Cognitive Level: Knowledge	REF:	10	
TOP:	Nursing Process Step: Assessment	
MSC:	NCLEX Client Needs Category: Safe, Effective Care Environment

	9.	Which statement is true about over-the-counter (OTC) drugs?
A.	They are not listed in the USP-NF.	
B.	A prescription from a health care provider is needed.	
C.	They are sold without a prescription.	
D.	They are known only by their brand names.	

ANS:	C

	Feedback	
A	OTC drugs are listed in the USP-NF.	
B	Prescription drugs require an order by a health professional who is licensed to prescribe, such as a physician, nurse practitioner, physician assistant, or dentist.	
C	OTC medications do not require a prescription.	
D	A variety of names, both generic and trade, can be used for individual drugs sold OTC.	

DIF:	Cognitive Level: Comprehension	REF:	2	
TOP:	Nursing Process Step: Planning	
MSC:	NCLEX Client Needs Category: Physiological Integrity

	10.	Which is the most authoritative reference for medications that are injected?
A.	Parenteral Drug Handbook	
B.	Handbook on Injectable Drugs	
C.	Drugs and Injections Quarterly	
D.	Handbook of Nonprescription Drugs	

ANS:	B

	Feedback	
A	There is not a reference by this name, and not all parenteral drugs are injected.	
B	The Handbook on Injectable Drugs is the most comprehensive reference available on the topic of compatibility of injectable drugs. It is a collection of monographs for more than 300 injectable drugs that are listed alphabetically by generic name.	
C	There is no reference by this name.	
D	This only has information about medications that do not require a prescription.	

DIF:	Cognitive Level: Comprehension	REF:	4	
TOP:	Nursing Process Step: Assessment	
MSC:	NCLEX Client Needs Category: Physiological Integrity

	11.	The nurse is administering Lomotil, a Schedule V drug. Which statement is true about this drug’s classification?
A.	Abuse potential for this drug is low.	
B.	Psychological dependency is likely.	
C.	There is a high potential for abuse.	
D.	This drug is not a controlled substance.	

ANS:	A

	Feedback	
A	Lomotil, a Schedule V drug, has an abuse potential of limited physical or psychological dependence liability compared with drugs in Schedule IV. Because abuse potential is low, a prescription may not be required.	
B	Psychological dependency is not likely with a Schedule V drug.	
C	The abuse potential is low with a Schedule V drug.	
D	Schedule V drugs are classified as controlled substances.	

DIF:	Cognitive Level: Knowledge	REF:	8	
TOP:	Nursing Process Step: Assessment	
MSC:	NCLEX Client Needs Category: Physiological Integrity

MULTIPLE RESPONSE

	1.	The nurse is caring for a patient newly diagnosed with type 1 diabetes mellitus. Which approaches to therapeutic methods are considered in this patient’s treatment? (Select all that apply.)
A.	Therapeutic drugs	
B.	Concentrated carbohydrate diet	
C.	Family-centered care	
D.	Regular daily exercise and activity	
E.	Daily baths	

ANS:	A, B, D

	Feedback	
Correct	Therapeutic methods include drug therapy.
Therapeutic methods include diet therapy.
Therapeutic methods include physiotherapy and psychological therapy.	
Incorrect	Therapeutic methods do not include family-centered care.
Therapeutic methods do not include daily baths.	

DIF:	Cognitive Level: Application	REF:	1	
TOP:	Nursing Process Step: Planning	
MSC:	NCLEX Client Needs Category: Physiological Integrity

	2.	An older adult experiencing shortness of breath is brought to the hospital by her daughter. While obtaining the medication history from the patient and her daughter, the nurse discovers that neither has a list of the patient’s current medications or prescriptions. All the patient has is a weekly pill dispenser that contains four different pills. The prescriptions are filled through the local pharmacy. Which resources are appropriate to use in determining the medication names and doses? (Select all that apply.)
A.	Martindale—The Complete Drug Reference	
B.	Physicians’ Desk Reference, Section 4	
C.	Senior citizens’ center	
D.	Patient’s home pharmacy	

ANS:	B, D

	Feedback	
Correct	The Physicians’ Desk Reference, Section 4, has full-color images of commonly dispensed tablets and capsules.
The patient’s pharmacy would have an accurate account of all the medications the client is currently taking.	
Incorrect	Martindale—The Complete Drug Reference has written information on medication and would not be an appropriate resource.
The senior citizens’ center is not likely to have specific patient medication information.	

DIF:	Cognitive Level: Application	REF:	5	
TOP:	Nursing Process Step: Assessment	
MSC:	NCLEX Client Needs Category: Physiological Integrity